VERAPAMIL AS A HYPOTENSIVE AGENT DURING NEUROLEPTANAE STHE S IA
Open Access
- 1 August 1981
- journal article
- research article
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 53 (8), 885-889
- https://doi.org/10.1093/bja/53.8.885
Abstract
The haemodynamic effects of verapaniil were investigated in 11 patients anaesthetized with thiopentone, fentanyl and dehydrobenzperidol. Suxamethonjpm and pancuronium bromide were used for muscle relaxation. Verapamil 0.07 mg–1 given as a single intravenous bolus decreased mean arterial pressure from 108±18mm Hg to 84±2OmmHg (P–1 (P<0.001) while heart rate and mean pulmonary artery pressure showed only minor changes. The decrease in arterial presstir was caused by reduction in total peripheral resistance while cardiac output was increased.Keywords
This publication has 3 references indexed in Scilit:
- Importance of heart rate in determining the effects of sympathomimetic amines on regional myocardial function and blood flow in conscious dogs with acute myocardial ischemia.Circulation Research, 1979
- Comparison of Nitroglycerin-, Nitroprusside-, and Phentolamine-Induced Changes in Coronary Collateral Function in DogsJCI Insight, 1977
- Die intrazelluläre Regulation der MuskelaktivitätThe Science of Nature, 1965