The action of certain drugs on the isolated human uterus

Abstract

I have elsewhere shown* that, in experiments on the isolated mammalian heart, it is perfectly possible to keep the exsected heart in cold Locke’s solution at ordinary room temperatures for hours and still to obtain powerful and regular contractions of the heart when, after this procedure, it is subsequently perfused with warm oxygenated Locke’s solution in the usual way. Similar observations have been made on other contractile tissues and will be dealt with in another communication. In the meantime, it is sufficient to point out that those observations open an easy way to experiments on a certain number of isolated human tissues, removed for surgical reasons, by which experiments certain questions can be answered which cannot readily, if at all, be decided in any other way.