Pain reduction by electrical brain stimulation in man
- 1 August 1977
- journal article
- research article
- Published by Journal of Neurosurgery Publishing Group (JNSPG) in Journal of Neurosurgery
- Vol. 47 (2), 178-183
- https://doi.org/10.3171/jns.1977.47.2.0178
Abstract
Acute studies performed in 5 patients indicated that electrical stimulation of the brain could be a powerful tool for the reduction or control of intractable pain. While chronic or spontaneous pain could be relieved by stimulation of the periaqueductal gray matter, the accompanying side effects rendered it impossible to stimulate this site regularly. Stimulation of medial thalamic sites, particularly medial to the nucleus parafascicularis, yielded good relief of chronic pain at parameters which did not cause many undesirable side effects. The same parameters also produced inhibition of acute pain in 2 of the 5 patients.This publication has 11 references indexed in Scilit:
- Monoaminergic mechanisms of stimulation-produced analgesiaBrain Research, 1975
- Pain reduction by focal electrical stimulation of the brain: An anatomical and behavioral analysisBrain Research, 1974
- Analgesia from electrical stimulation of the periaqueductal gray matter in the cat: behavioral observations and inhibitory effects on spinal cord interneuronsBrain Research, 1973
- Antagonism of stimulation-produced analgesia by p-CPA, a serotonin synthesis inhibitorBrain Research, 1972
- Analgesia from Electrical Stimulation in the Brainstem of the RatScience, 1971
- Mesencephalic central gray lesions and fear-motivated behavior in ratsBrain Research, 1970
- Surgery in the Rat during Electrical Analgesia Induced by Focal Brain StimulationScience, 1969
- Sensations Evoked by Stimulation in the Midbrain of ManJournal of Neurosurgery, 1969
- Relief of pain by electrical stimulation of the septal areaJournal of the Neurological Sciences, 1967
- Thalamotomy for Intractable PainStereotactic and Functional Neurosurgery, 1967