Coronary artery occlusion in the intact unanesthetized dog: intercoronary reflexes

Abstract

A 20- to 30-sec. occlusion of the descendens coronary artery in conscious dogs well-recovered from surgery decreased mildly cardiac output, stroke volume, and myocardial contractility. There was a delayed increase in phasic circumflex coronary flow and a decrease in mean coronary resistance and end-diastolic coronary resistance. Various drugs did not alter this over-all response pattern. Evidence of a vasoconstrictor reflex could not be demonstrated in these experiments.