Development of ductal carcinoma of the pancreas during follow-up of branch duct intraductal papillary mucinous neoplasm of the pancreas
Top Cited Papers
- 13 May 2008
- Vol. 57 (11), 1561-1565
- https://doi.org/10.1136/gut.2007.145631
Abstract
Background: Synchronous occurrence of intraductal papillary mucinous neoplasm (IPMN) and ductal carcinoma of the pancreas has been reported. Branch duct IPMNs with lower likelihood of malignancy are not submitted to resection but are followed-up, so ductal carcinoma may develop during the follow-up. The development of ductal carcinoma of the pancreas during follow-up of branch duct IPMNs was investigated. Methods: 60 patients with branch duct IPMN who had an intraductal tumour of 70 years old developed ductal carcinoma significantly more frequently than those under 69. Four of five ductal carcinomas identified during follow-up were resectable. Cancer developed in IPMN in 2 of 60 (3%) branch duct IPMNs during follow-up. Conclusions: During follow-up of branch duct IPMNs, ductal carcinoma of the pancreas not infrequently developed distinct from IPMN. In the follow-up of IPMN, special attention should be paid to the development of ductal carcinoma of the pancreas.Keywords
This publication has 27 references indexed in Scilit:
- Branch-duct intraductal papillary mucinous neoplasms of the pancreas: to operate or not to operate?Gut, 2007
- Incidence of Additional Primary Cancers in Patients with Invasive Intraductal Papillary Mucinous Neoplasms and Sporadic Pancreatic AdenocarcinomasJournal of the American College of Surgeons, 2007
- Clinicopathological features and medical management of intraductal papillary mucinous neoplasmsJournal of Gastroenterology and Hepatology, 2006
- Pancreatic juice cytology in the diagnosis of intraductal papillary mucinous neoplasm of the pancreasCancer, 2005
- Mode of progression of intraductal papillary-mucinous tumor of the pancreas: analysis of patients with follow-up by EUSThe Esophagus, 2005
- Diagnosis and management of cystic pancreatic tumours with mucin productionBritish Journal of Surgery, 2000
- Intraductal Papillary Mucinous Tumors of the PancreasAnnals of Surgery, 1998
- Pancreatic Mucinous Ductal Ectasia and Intraductal Papillary NeoplasmsAnnals of Surgery, 1997
- Intraductal papillary-mucinous tumors of the pancreas: Clinicopathologic features, outcome, and nomenclature. Members of the Pancreas Clinic, and Pancreatic Surgeons of Mayo ClinicGastroenterology, 1996
- Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genesCell, 1988