Abstract
Two patients with probable bacterial endocarditis due to a coagulase-positive Staphylococcus aureus developed Candida albicans infection of the blood stream while under treatment for their bacterial infection with massive amounts of broad-spectrum antibiotics. Several antemortem blood cultures were positive in both instances for C. albicans. The 1st patient died rapidly from the superimposed systemic fungus infection. The 2d patient was successfully treated for the C. albicans septicemia by the use of crystalline Mycostatin (mystatin) administered intramuscularly.