Fletcher Factor Activity in Plasmas of Various Species
- 1 November 1974
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 147 (2), 519-523
- https://doi.org/10.3181/00379727-147-38378
Abstract
The plasmas of 18 species were assayed for Fletcher factor activity using human Fletcher trait plasma as a substrate. Ape, swine, guinea pig and mouse plasmas had Fletcher factor activity comparable to that of human plasma. In contrast, bovine, dog, cat, rabbit and cetacean plasmas contained almost no Fletcher factor. In immunodiffusion studies using rabbit anti-human kallikrein (Fletcher factor) serum, only human and ape plasmas gave a precipitin line. There is a good correlation between Fletcher factor activity tested on human substrates and kaolin-activated TAMe esterase levels of each species' own plasma at 1 min incubation.This publication has 3 references indexed in Scilit:
- The Kallikreinogen-Kallikrein Enzyme System of Human PlasmaAnnals of Internal Medicine, 1969
- Evidence for a New Plasma Thromboplastin Factor I. Case Report, Coagulation Studies and Physicochemical PropertiesBlood, 1965
- The Purification of Activated Hageman Factor (Activated Factor XII)*Biochemistry, 1962