Enantioselective conjugate addition of diethylzinc to enones catalyzed by a copper complex of chiral aryl diphosphite

Abstract

The 1,4-conjugate addition of diethylzinc to cyclohex-2-enone and cyclopent-2-enone catalyzed by a copper complex of a chiral aryl diphosphite gave the desired products with 90.2 and 76.6% ee respectively.