Generalized Shwartzman Reaction in the Pregnant Golden Hamster
- 8 March 1963
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 139 (3558), 923-924
- https://doi.org/10.1126/science.139.3558.923
Abstract
A single intraperitoneal injection of colchicine regularly elicits the generalized Shwartzman phenomenon in the pregnant golden hamster. Non-pregnant hamsters are refractory both to colchicine and endotoxin. The superiority of colchicine, as opposed to foreign endotoxin, in the pregnant subject, may be attributed to the action of native endotoxin which is allowed parenteral access as a result of colchicine-induced injury to the intestinal mucosa.Keywords
This publication has 6 references indexed in Scilit:
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- STUDIES OF THE GENERALIZED SHWARTZMAN REACTION PRODUCED BY DIETThe Journal of Experimental Medicine, 1962
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- The pathologic anatomy of eclampsia, bilateral renal cortical necrosis, pituitary necrosis, and other acute fatal complications of pregnancy, and its possible relationship to the generalized Shwartzman phenomenonAmerican Journal of Obstetrics and Gynecology, 1953
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