Zwischenfälle bei der Fluoreszenzangiografie der Retina. Symptomatik, Prophylaxe und Therapie

Abstract

The pathomecanism of the fluorescein incident is described. The anaphylactic reaction is, in accordance with the "all-or-nothing law", independent of the dose. Antihistamines and corticosteroides should be given prophylactically. Severe reactions require anesthesiological treatment. Fluorescein angiography of the retina should be performed only if an anesthesiologist is available. Fluorescein incidents - anaphylactic or anaphylactoid reactions - are very rare (0.1-1.1%). It is estimated that in every 20 000 procedures only one incident endangering life occurs. Fluorescein angiography of the retina should be performed only when the indication is utterly justified and then only if it will provide a guide for treatment. If prophylactic and therapeutic measures can be taken immediately the risk of fluorescein angiography is acceptable.