Genetic variation at a pig serum protein locus, Po‐2 and its assignment to the Phi, Hal, S, H, Pgd linkage group
- 1 January 1983
- journal article
- research article
- Published by Wiley in Animal Blood Groups and Biochemical Genetics
- Vol. 14 (1), 27-36
- https://doi.org/10.1111/j.1365-2052.1983.tb01057.x
Abstract
Two-dimensional agarose gel(pH 5.4)-polyacrylamide gel (pH 9.0) electrophoresis of pig serum samples revealed a new serum protein (postalbumin-2, PO-2) polymorphism. Family data supported the hypothesis that the 3 PO-2 phenotypes observed were controlled by 2 codominant, autosomal alleles (Po-2F and Po-2S) at a single locus. The frequency of Po-2F in Swedish Landrace and in Swedish Yorkshire breeds was estimated at 0.74 and 0.65, respectively. Evidence was presented for close genetic linkage between Po-2 and the red cell phosphohexose isomerase locus (Phi). A recombination frequency of 3.2% was obtained from double backcross material. Data obtained in a Danish Landrace material showing linkage between the Po-2 locus and the H blood group locus, the Pgd locus and Hal (locus for halothane sensitivity) are also given. A total of 7 recombinations were observed. Po-2 is a new locus in a previously established linkage group. The likely sequence of the loci is: Phi, Hal, S, H, Po-2, Pgd.Keywords
This publication has 16 references indexed in Scilit:
- Two-dimensional gel electrophoresis of cattle plasma proteins: Genetic polymorphism of an α1-protease inhibitorAnimal Blood Groups and Biochemical Genetics, 2009
- Genetic polymorphism and close linkage of two α1-protease inhibitors in horse serumAnimal Blood Groups and Biochemical Genetics, 2009
- Linkage of genes for PHI, halothane sensitivity, A-O inhibition, H red blood cell antigens and 6-PGD variants in pigs*Animal Blood Groups and Biochemical Genetics, 2009
- Polymorphic serum prealbumin (Pa) of pig, identified as an a!-protease inhibitorAnimal Blood Groups and Biochemical Genetics, 2009
- A new genetically determined plasma protein polymorphism in the laboratory rabbitHereditas, 2009
- Population studies ofPhi, Hal, Hhaplotype frequencies and linkage disequilibria in Danish Landrace pigsZeitschrift für Tierzüchtung und Züchtungsbiologie, 1981
- Halothane sensitivity and linkage of genes for H red blood cell antigens, phosphohexose isomerase (PHI) and 6‐phosphogluconate dehydrogenase (6‐PGD) variants in pigs*Animal Blood Groups and Biochemical Genetics, 1980
- Inheritance of reaction to halothane anaesthesia in pigsGenetics Research, 1977
- H Blood Types in Pigs as Predictors of Stress SusceptibilityScience, 1976
- Linear sequence of the autosomal loci PHI, H and 6‐PGD in pigs1Animal Blood Groups and Biochemical Genetics, 1971