LATE CEREBRAL SEQUELAE OF RHEUMATIC FEVER
- 31 May 1944
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Internal Medicine
- Vol. 73 (6), 472-476
- https://doi.org/10.1001/archinte.1944.00210180044006
Abstract
Until recently, rheumatic fever has been viewed as a disease taking place within a short period. The newer concepts, however, emphasize that the rheumatic infection may endure through the entire life of the patient. Mental symptoms during acute rheumatic fever have been observed since the days of Benjamin Rush, founder of American psychiatry.1 Mental disease occurring within a period of several months following the acute stage, as the result of rheumatic cerebral involvement, has been described by Winkelman and Eckel.2 A woman aged 33 had rheumatic fever. She recovered sufficiently to be able to do light house work. Several months later she began to have ideas of persecution, visual hallucinations and suicidal tendencies. When she died, shortly afterward, microscopic examination of the brain revealed proliferative endarteritis of the small cortical vessels and minute areas of partial and complete softening in the gray matter. More recent neuropathologic studies3This publication has 4 references indexed in Scilit:
- RHEUMATIC EPILEPSYAmerican Journal of Psychiatry, 1942
- ASSOCIATION BETWEEN CONVULSIVE SEIZURES AND RHEUMATIC HEART DISEASEArchives of Neurology & Psychiatry, 1942
- Lesions of the coronary arteries and their branches in rheumatic fever1935
- Specific lesions of peripheral blood vessels in rheumatism1926