Amylase‐producing lung cancer

Abstract

A bronchioloalveolar carcinoma of lung associated with hyper‐amylasemia occurring in a 40‐year‐old woman is described. Another 13 cases of such a tumor from the English literature are reviewed. A majority of the lung tumors associated with hyperamylasemia were adenocarcinomas. When the amylase isoenzymes were determined, the amylase appeared to be salivary‐gland type (S‐type). Electron microscopic studies had revealed membrane‐bound electron‐dense granules within the tumor cells.