Effect of oligosaccharide chain length, exposed terminal group, and hapten loading on the antibody response of human adults and infants to vaccines consisting of Haemophilus influenzae type b capsular antigen unterminally coupled to the diphtheria protein CRM197.
Open Access
- 1 April 1989
- journal article
- research article
- Published by The American Association of Immunologists in The Journal of Immunology
- Vol. 142 (7), 2464-2468
- https://doi.org/10.4049/jimmunol.142.7.2464
Abstract
Vaccines consisting of oligosaccharide (OS) derived from Haemophilus influenzae type b capsular polysaccharide and conjugated to carrier proteins hadThis publication has 13 references indexed in Scilit:
- Immunogenicity of Haemophilus influenzae type b polysaccharide—diphtheria toxoid conjugate vaccine in adultsThe Journal of Pediatrics, 1984
- Immunogenic Properties of α(1 → 6) Dextran, Its Protein Conjugates, and Conjugates of Its Breakdown Products in MiceScandinavian Journal of Immunology, 1984
- 31 P- and 13 C-N.M.R.-spectral and chemical characterization of the end-group and repeating-unit components of oligosaccharides derived by acid hydrolysis of haemophilus influenzae type b capsular polysaccharideCarbohydrate Research, 1983
- Comparison of the induction of immunoglobulin M and G antibodies in mice with purified pneumococcal type 3 and meningococcal group C polysaccharides and their protein conjugatesInfection and Immunity, 1982
- The immune response to an isomaltohexosyl-protein conjugate, a thymus-dependent analogue of alpha(1 replaced by 6) dextran.The Journal of Immunology, 1982
- Immunochemistry of groups A, B, and C meningococcal polysaccharide-tetanus toxoid conjugates.The Journal of Immunology, 1981
- Phenotypic and Genetic Variation in the Susceptibility of Haemophilus influenzae Type b to Antibodies to Somatic AntigensJCI Insight, 1980
- Immunochemistry of Salmonella O-Antigens: Specificity of Rabbit Antibodies against the O-Antigen 4 Determinant Elicited by Whole Bacteria and O-Antigen 4 Specific Saccharide-Protein ConjugatesThe Journal of Immunology, 1979
- Immunochemical properties of oligosaccharide-protein conjugates withKlebsiella-K2 specificityMedical Microbiology and Immunology, 1979
- Intrinsic Tritium Labeling of the Capsular Polysaccharide Antigen of Haemophilus Influenzae Type BThe Journal of Immunology, 1978