Cholesterol and bile salt studies on the bile of patients with cholesterol gallstones
Open Access
- 1 February 1973
- Vol. 14 (2), 83-88
- https://doi.org/10.1136/gut.14.2.83
Abstract
Gallbladder bile from patients with cholesterol stones and control patients without cholesterol stones was analysed for the relative concentrations of bile salts, phospholipids, and cholesterol. It was not possible to distinguish stone-forming from control biles when these were plotted on triangular coordinates. There was a significant increase in the dihydroxy: trihydroxy bile salt ratio in the patients with cholesterol gallstones. The maximum cholesterol holding capacity for the bile salts was determined and no difference could be detected in the ability of the bile salts from either cholesterol stone-containing and control bile samples to dissolve cholesterol.Keywords
This publication has 25 references indexed in Scilit:
- Lithogenic bile in patients with ileal dysfunctionGut, 1972
- Dissolution of Cholesterol Gallstones by Chenodeoxycholic AcidNew England Journal of Medicine, 1972
- The solubility of cholesterol in aqueous solutions of bile salts and lecithinZeitschrift Fur Ernahrungswissenschaft, 1971
- Studies on human bileZeitschrift Fur Ernahrungswissenschaft, 1971
- Lithogenic Bile among Young Indian WomenNew England Journal of Medicine, 1971
- The cholesterol solubilizing capacity of lecithins in aqueous solutions of bile saltBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1969
- GallstonesNew England Journal of Medicine, 1968
- Cholesterol Solubilization by Solutions of Bile Salts and Bile Salts Plus LecithinExperimental Biology and Medicine, 1968
- The physicochemical basis of cholesterol gallstone formation in manJCI Insight, 1968
- A simple method for the determination of serum cholesterolClinica Chimica Acta; International Journal of Clinical Chemistry, 1960