The tubulogenic activity associated with an activated form of Flt-1 kinase is dependent on focal adhesion kinase
- 14 August 2001
- journal article
- Published by Elsevier in Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
- Vol. 1540 (2), 147-153
- https://doi.org/10.1016/s0167-4889(01)00127-6
Abstract
No abstract availableKeywords
This publication has 19 references indexed in Scilit:
- Roles of two VEGF receptors, Flt-1 and KDR, in the signal transduction of VEGF effects in human vascular endothelial cellsOncogene, 2000
- Vascular Endothelial Growth Factor (VEGF)-driven Actin-based Motility Is Mediated by VEGFR2 and Requires Concerted Activation of Stress-activated Protein Kinase 2 (SAPK2/p38) and Geldanamycin-sensitive Phosphorylation of Focal Adhesion KinaseJournal of Biological Chemistry, 2000
- FAK integrates growth-factor and integrin signals to promote cell migrationNature Cell Biology, 2000
- An oncogenic form of the Flt-1 kinase has a tubulogenic potential in a sinusoidal endothelial cell lineEuropean Journal of Cell Biology, 2000
- Induced Focal Adhesion Kinase (FAK) Expression in FAK-Null Cells Enhances Cell Spreading and Migration Requiring Both Auto- and Activation Loop Phosphorylation Sites and Inhibits Adhesion-Dependent Tyrosine Phosphorylation of Pyk2Molecular and Cellular Biology, 1999
- Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in miceProceedings of the National Academy of Sciences, 1998
- Flt-1, a receptor for vascular endothelial growth factor, has transforming and morphogenic potentialsOncogene, 1998
- Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient miceNature, 1995
- Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endotheliumNature, 1995
- Failure of blood-island formation and vasculogenesis in Flk-1-deficient miceNature, 1995