The reflex grasping produced in the infant by introducing the finger into its palm is a phenomenon too well known to deserve description. It disappears as the child develops, probably at about the age of 1 year, although the exact time is variable. This phenomenon may appear in later life as a manifestation of disease of the brain either focal or general. In certain cases it is of definite localizing value, pointing accurately to the contralateral frontal lobe. Only within the past year has the symptom evoked much attention or discussion, although its nature seems to have been recognized by Janischewsky1as much as twenty years ago. His extensive contribution last year, appearing almost simultaneously with those of Schuster,2and of Adie and Critchley,3has served to focus the attention of neurologists on what appears to be a valuable sign in cerebral localization. There is abundant evidence,