Platelets and tissue factor
- 1 September 2005
- journal article
- review article
- Published by Taylor & Francis in Platelets
- Vol. 16 (6), 313-319
- https://doi.org/10.1080/09537100500140190
Abstract
Tissue factor (TF) is the most important initiator of intravascular coagulation. This article will review published evidence on the contribution of platelets to TF exposure to the circulating blood. The following mechanisms will be discussed: Decryption of monocyte TF by platelets, contribution of platelets to TF expression in leukocytes, platelet-derived TF and its procoagulant activity, and activation of circulating TF by platelets.Keywords
This publication has 70 references indexed in Scilit:
- Role of P-selectin and PSGL-1 in coagulation and thrombosisThrombosis and Haemostasis, 2004
- Abciximab Reduces Monocyte Tissue Factor in Carotid Angioplasty and StentingStroke, 2003
- Platelet Activation Induces Cell-Surface Immunoreactive Tissue Factor Expression, Which Is Modulated Differently by Antiplatelet DrugsArteriosclerosis, Thrombosis, and Vascular Biology, 2003
- Characterization of platelet-specific mRNA by real-time PCR after laser-assisted microdissectionThrombosis and Haemostasis, 2003
- Platelet-leukocyte aggregation under shear stress: Differential involvement of selectins and integrinsThrombosis and Haemostasis, 2003
- Platelet-Associated Tissue Factor Contributes to the Collagen-Triggered Activation of Blood CoagulationBiochemical and Biophysical Research Communications, 2001
- CD40 Ligation Induces Tissue Factor Expression in Human Vascular Smooth Muscle CellsThe American Journal of Pathology, 2000
- Receptors and signalling mechanisms in the procoagulant response of plateletsPlatelets, 2000
- 12‐Hydroxyeicosatetraenoic acid upregulates P‐selectin‐induced tissue factor activity on monocytesFEBS Letters, 1998
- The cytokine‐mediated imbalance between coagulant and anticoagulant mechanisms in sepsis and endotoxaemiaEuropean Journal of Clinical Investigation, 1997