Intracellular cargo delivery using tat peptide and derivatives
- 15 September 2003
- journal article
- review article
- Published by Wiley in Medicinal Research Reviews
- Vol. 24 (1), 1-12
- https://doi.org/10.1002/med.10056
Abstract
Efficient delivery of therapeutic and diagnostic agents across the plasma membrane is crucial in developing novel therapies. Membrane permeating peptides, in particular HIV‐1 tat peptide and its derivatives, have enabled the intracellular delivery of cargos of various sizes and physicochemical properties. This review summarizes the current knowledge of tat‐derived cell permeating peptides in the transduction of exogenous molecules/complexes. © 2003 Wiley Periodicals, Inc. Med Res Rev, 24, No. 1, 1–12, 2004Keywords
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