BLOOD PRESSURE AND PULSE RESPONSE TO INSULIN‐INDUCED HYPOGLYCEMIA DURING NON‐SELECTIVE AND SELECTIVE β‐BLOCKADE

Abstract

Hypoglycemia was induced in ten healty male volunteers during medication with atenolol, metoprolol and propranolol. The β‐blockers abolished the tachycardia during hypoglycemia. In some subjects bradycardia, and in two nodal bradycardia was observed on propranol. The physiologic blood pressure responses were dam‐pend during the β₁‐selective blockade. With propranolol a rise in blood pressure was recorded, in two subjects up to 160/105. The blockers had no effect on degree of hypoglycemia or glucose recovery.