A plasmid DNA primase active in discontinuous bacterial DNA replication

Abstract
A DNA primase encoded by an IncI.alpha. plasmid promotes efficient DNA replication in a primase-defective mutant of Escherichia coli. The plasmid enzyme can apparently prime discontinuous DNA synthesis of the bacterial chromosome. The plasmid gene encodes 2 large, antigenically related proteins which differ from E. coli primase.