On paternity determination from multilocus DNA profiles

Abstract

Various approaches have been worked out to calculate to the probability of paternity from DNA multilocus profiles. Despite promising results, the application and practicability of these approaches are often restricted (due to, e.g., the equality assumption of the a priori probabilities by using Bayes theorem, no allowance of mutations, etc). Here we present two methods for paternity determination, one of which is an extension of the well-known procedure of Evett et al. J. Forens. Sci. Soc. 1988, 28, 249–254. These methods depend on fewer assumption sand therefore maybe applied to a wide spectrum of disputed paternity cases.