Influence of Hypophysectomy and Growth Hormone on Cartilage Sulfate Metabolism.
- 1 December 1953
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 84 (3), 603-605
- https://doi.org/10.3181/00379727-84-20726
Abstract
Hypophysectomy of immature growing rats at 26 days of age resulted in a decrease of S35 uptake by costal cartilage to 11% of normal as revealed by specific activity ratios of cartilage to plasma inorganic sulfate. The injn. of 75 [mu]g. of growth hormone restored the ratio to 33% of normal. The specific activity of plasma inorganic sulfate of hypophysectomized rats was several fold higher than that of normal rats, and growth hormone produced a lowering toward normal.Keywords
This publication has 4 references indexed in Scilit:
- THE EFFECT OF GROWTH HORMONE ON TIBIA GLYCOGEN CONTENT OF THE HYPOPHYSECTOMIZED RAT1Endocrinology, 1953
- ON THE ENZYMATIC EXCHANGE OF THE SULFATE GROUP OF CHONDROITINSULFURIC ACID IN SLICES OF CARTILAGEJournal of Biological Chemistry, 1952
- BIOASSAY OF HYPOPHYSEAL GROWTH HORMONE: THE TIBIA TEST1Endocrinology, 1949
- ON THE POSSIBLE UTILIZATION OF SULFATE SULFUR BY THE SUCKLING RAT FOR THE SYNTHESIS OF CHONDROITIN SULFATE AS INDICATED BY THE USE OF RADIOACTIVE SULFURJournal of Biological Chemistry, 1949