Single base deletion in the vasopressin gene is the cause of diabetes insipidus in Brattleboro rats
- 1 April 1984
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 308 (5961), 705-709
- https://doi.org/10.1038/308705a0
Abstract
In rats with hereditary hypothalamic diabetes insipidus (Brattleboro rats) the gene for the vasopressin precursor lacks a single G residue in the protein-coding region. The mutation gives rise to an open reading frame predicting a hormone precursor having a different C-terminus.Keywords
This publication has 22 references indexed in Scilit:
- Deduced amino acid sequence from the bovine oxytocin–neurophysin I precursor cDNANature, 1983
- Precursors of Vasopressin and OxytocinPublished by Elsevier ,1983
- THE DISCOVERY OF THE BRATTLEBORO RAT, RECOMMENDED NOMENCLATURE, AND THE QUESTION OF PROPER CONTROLS*Annals of the New York Academy of Sciences, 1982
- Immunohistochemical localization of human pituitary glycopeptide (HPGP)-like immunoreactivity in the hypothalamus and pituitary of normal and homozygous diabetes insipidus (Brattleboro) rats.Journal of Histochemistry & Cytochemistry, 1982
- BIOCHEMICAL AND FUNCTIONAL ASPECTS OF MAGNOCELLULAR NEURONS AND HYPOTHALAMIC DIABETES INSIPIDUSAnnals of the New York Academy of Sciences, 1982
- Nucleotide sequence of cloned cDNA encoding bovine arginine vasopressin–neurophysin II precursorNature, 1982
- Synthesis, Transport, and Release of Posterior Pituitary HormonesScience, 1980
- [57] Sequencing end-labeled DNA with base-specific chemical cleavagesMethods in Enzymology, 1980
- A general method for isolation of high molecular weight DNA from eukaryotesNucleic Acids Research, 1976
- Detection of specific sequences among DNA fragments separated by gel electrophoresisJournal of Molecular Biology, 1975