The Development and Use of the Prothrombin Tests
- 1 January 1959
- journal article
- editorial
- Published by Wolters Kluwer Health in Circulation
- Vol. 19 (1), 92-96
- https://doi.org/10.1161/01.cir.19.1.92
Abstract
A historical account of the development of the 1- and 2-stage prothrombin tests is presented and the influence of the classical theory of coagulation is indicated. The work which led to the preparation of a standardized thromboplastin reagent is briefly described. The clinical application of the 1-stage method to the bleeding in obstructive jaundice and in the newborn is mentioned.Keywords
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