Acute dietary effects on plasma lipids, lipoproteins and lipolytic enzymes in healthy normal males

Abstract

Diurnal plasma lipids and lipoproteins were studied in 12 healthy young males on corn oil and palm oil diets, respectively. The major triglyceride fatty acids were determined serially in the lipoprotein classes during the day. Lecithin-cholesterol acyl transferase, lipoprotein lipase and hepatic triglyceride lipase were measured. Diurnal changes of triglycerides and cholesterol were confined to lipoproteins of d [density] < 1.006 kg/l. There was a diurnal rise of lecithin-cholesterol acyl transferase activity with corn oil but not with palm oil. Fasting and postprandial postheparin lipoprotein lipase and hepatic triglyceride lipase were similar but there was a significant correlation of postprandial hepatic lipase with postprandial plasma triglycerides on palm oil. Marked diurnal changes of triglyceride fatty acids were observed in very low density lipoprotein and in high-density lipoprotein amounting to .apprxeq. 1/3 of total high density lipoprotein triglyceride fatty acids.