Linkage in Size Inheritance

Abstract

An analysis of the data on the back-cross generation of a mouse species cross, between large Mus musculus with 3 recessive color characters (dba) and small M. bactrianus with the 3 dominant allelomorphs (DBA W), has unquestionably shown an association in heredity between factors productive of a large final size in several quantitative characters and a qualitative, brown. This association, found to be statistically significant in four of the 9 adult size characters, was interpreted as genetic linkage and considered as proof that size in mice is influenced by chromosomal genes. To a lesser extent, size in two characters seems to be affected by factors linked with dilution.