Effects of tobacco smoke extracts on collagen biosynthesis by fibroblast cell cultures
- 1 May 1982
- journal article
- research article
- Published by Taylor & Francis in Journal of Toxicology and Environmental Health
- Vol. 9 (5-6), 921-932
- https://doi.org/10.1080/15287398209530214
Abstract
The effects of tobacco smoke extracts on collagen and total protein synthesis by [human skin] fibroblast cell cultures were studied. Tobacco extract with a nicotine concentration of 35 nmol/ml culture medium increased collagen production but not protein secretion in the culture medium. Not only the rate of collagen synthesis but also the types of collagen produced were affected; there was a decrease of type 3 collagen.This publication has 13 references indexed in Scilit:
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