Immunohistochemical demonstration of catecholaminergic cell bodies in the spinal cord of the rat
- 1 January 1985
- journal article
- research article
- Published by Springer Nature in Histochemistry and Cell Biology
- Vol. 82 (4), 385-389
- https://doi.org/10.1007/bf00494068
Abstract
In order to elucidate the anatomy of the spinal dopaminergic system, an immunohistochemical study using a tyrosine-hydroxylase (TH) antibody was undertaken in the rat. Intracisternal 6-hydroxydopamine (6-OHDA) injections were administered to destroy most of the noradrenergic fibres that descende to the spinal cord while preserving the dopaminergic fibres. The density of the remaining TH-like immunoreactive fibres was relatively low at all levels of the spinal cord; the highest density was observed in layers III, IV and X. In addition, we report the first evidence for the existence of TH-like immunoreactive cell bodies at definite levels (especially sacral) of the spinal cord.Keywords
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