Catheter-directed low dose streptokinase infusion: a preliminary experience.
- 1 February 1984
- journal article
- research article
- Published by Radiological Society of North America (RSNA) in Radiology
- Vol. 150 (2), 349-355
- https://doi.org/10.1148/radiology.150.2.6691087
Abstract
Patients (56) with acute or chronic arterial or venous thromboembolic occlusions received treatment with low dose (5000 U/h) streptokinase via an indwelling intravascular catheter. Successful clot lysis was achieved in 13 of 14 (92%) postprocedural occlusions that were < 1 wk in age, in 8 of 11 (73%) atherosclerotic occlusions that were < 6 wk in age, in 2 of 3 (67%) emboli from cardiac thrombi and in all of the pulmonary emboli and superior vena cava occlusions. In the chronic occlusions, successful thrombus lysis occurred less frequently (8 of 21, 38%). Although the initial objective of fibrinolytic therapy is clot lysis, the long term clinical success depends on the diagnosis and treatment of the underlying cause of the thromboembolism.This publication has 4 references indexed in Scilit:
- Pharmacology of angioplasty and intravascular thrombolysisAmerican Journal of Roentgenology, 1982
- Low-dose intravascular fibrinolytic therapy.Radiology, 1982
- Low dose streptokinase in the treatment of arterial occlusionsAmerican Journal of Roentgenology, 1981
- Thrombolytic Therapy in Thrombosis: A National Institutes of Health Consensus Development ConferenceAnnals of Internal Medicine, 1980