Solid phase synthesis of peptide vinyl sulfone and peptide epoxyketone proteasome inhibitors
- 5 August 2000
- journal article
- research article
- Published by Elsevier in Tetrahedron Letters
- Vol. 41 (32), 6005-6009
- https://doi.org/10.1016/s0040-4039(00)00968-0
Abstract
No abstract availableKeywords
This publication has 15 references indexed in Scilit:
- Proteasome inhibition by the natural products epoxomicin and dihydroeponemycin: Insights into specificity and potencyBioorganic & Medicinal Chemistry Letters, 1999
- Towards subunit-specific proteasome inhibitors: synthesis and evaluation of peptide α', β'-epoxyketonesChemistry & Biology, 1999
- Total synthesis of the-potent proteasome inhibitor epoxomicin: a useful tool for understanding proteasome biologyBioorganic & Medicinal Chemistry Letters, 1999
- The 26S Proteasome: A Molecular Machine Designed for Controlled ProteolysisAnnual Review of Biochemistry, 1999
- Proteasome inhibitors: valuable new tools for cell biologistsTrends in Cell Biology, 1998
- Potent and selective inhibitors of the proteasome: Dipeptidyl boronic acidsBioorganic & Medicinal Chemistry Letters, 1998
- Covalent modification of the active site threonine of proteasomal β subunits and theEscherichia colihomolog HslV by a new class of inhibitorsProceedings of the National Academy of Sciences, 1997
- Proteasomes of the yeastS. cerevisiae: genes, structure and functionsMolecular Biology Reports, 1995
- Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I moleculesCell, 1994
- γ-Interferon and expression of MHC genes regulate peptide hydrolysis by proteasomesNature, 1993