Blood pressure lowering action of adenosine diphosphate and related compounds
- 30 November 1961
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 201 (6), 1123-1125
- https://doi.org/10.1152/ajplegacy.1961.201.6.1123
Abstract
It was found upon intravenous injection of adenosine and its mono-, di-, and triphosphate in the rat that ADP produced the greatest fall in arterial blood pressure. At low dose levels ADP was about 147 times as potent as adenosine and about 45 times as potent as AMP or ATP on an equimolar basis. The rat is more sensitive to the blood pressure lowering action of the adenosine compounds than other species thus far tested.Keywords
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