Fertilization: A Uterine Glycosaminoglycan Stimulates the Conversion of Sperm Proacrosin to Acrosin
- 9 February 1979
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 203 (4380), 553-554
- https://doi.org/10.1126/science.32621
Abstract
Acrosin is a proteinase required for mammalian fertilization, and in freshly ejaculated spermatozoa exists as an inactive zymogen, proacrosin. A factor prsent in uterine flushings of gilts stimulates the conversion of highly pruified boar proacrosin to acrosin. Characterization of this factor indicates that its active component is a glycosaminoglycan.This publication has 13 references indexed in Scilit:
- Boar proacrosin. Purification and preliminary activation studies of proacrosin isolated from ejaculated boar sperm.Journal of Biological Chemistry, 1977
- Benzamidine as an inhibitor of proacrosin activation in bull spermBiochimica et Biophysica Acta (BBA) - Enzymology, 1977
- [26] ProacrosinMethods in Enzymology, 1976
- Proacrosin from Rabbit Epididymal Spermatozoa: Partial Purification and Initial Biochemical Characterization1Biology of Reproduction, 1975
- Biochemistry of Mammalian FertilizationAnnual Review of Biochemistry, 1974
- Sperm Capacitation and Fertilization in MammalsBiology of Reproduction, 1970
- SPERM PENETRATION OF PIG EGGS IN RELATION TO THE TIMING OF OVULATION AND INSEMINATIONReproduction, 1968
- ENDOMETRIAL SECRETIONS*Annals of the New York Academy of Sciences, 1963
- The Mechanism of Action of HyaluronidasesJournal of Biological Chemistry, 1961
- Metachromasia in the endometriumAmerican Journal of Obstetrics and Gynecology, 1950