Epithelial calcium channel: gate-keeper of active calcium reabsorption
- 1 July 2000
- journal article
- review article
- Published by Wolters Kluwer Health in Current Opinion in Nephrology and Hypertension
- Vol. 9 (4), 335-340
- https://doi.org/10.1097/00041552-200007000-00003
Abstract
The epithelial calcium channel present in the apical membrane of 1,25-dihydroxyvitamin D3-responsive nephron segments represents the first member of a new family of calcium channels. This review covers the distinctive properties of this highly calcium-selective channel and highlights the implications for our understanding of the process of calcium reabsorption.Keywords
This publication has 27 references indexed in Scilit:
- Permeation and Gating Properties of the Novel Epithelial Ca2+ ChannelJournal of Biological Chemistry, 2000
- Purinergic activation of spontaneous transient outward currents in guinea pig taenia colonic myocytesAmerican Journal of Physiology-Cell Physiology, 2000
- Mammalian Distal Tubule: Physiology, Pathophysiology, and Molecular AnatomyPhysiological Reviews, 2000
- Molecular Cloning of an N-terminal Splice Variant of the Capsaicin ReceptorPublished by Elsevier ,2000
- The Epithelial Calcium Channel, ECaC, Is Activated by Hyperpolarization and Regulated by Cytosolic CalciumBiochemical and Biophysical Research Communications, 1999
- Translocation of a calcium-permeable cation channel induced by insulin-like growth factor-INature Cell Biology, 1999
- A capsaicin-receptor homologue with a high threshold for noxious heatNature, 1999
- Molecular Identification of the Apical Ca2+Channel in 1,25-Dihydroxyvitamin D3-responsive EpitheliaJournal of Biological Chemistry, 1999
- The capsaicin receptor: a heat-activated ion channel in the pain pathwayNature, 1997
- Cellular calcium transport in renal epithelia: measurement, mechanisms, and regulationPhysiological Reviews, 1995