Saethre-Chotzen Syndrome Associated with Defective Neutrophil Chemotaxis
- 1 March 1990
- journal article
- case report
- Published by Wiley in Acta Paediatrica
- Vol. 79 (3), 375-379
- https://doi.org/10.1111/j.1651-2227.1990.tb11477.x
Abstract
An 11-month-old male infant with Saethre-Chotzen syndrome and recurrent respiratory infections is described. Persistent extremely high leukocytosis warranted evaluation of neutrophil functions. It was found that the opsonophagocytic activity was normal, but neutrophil chemotaxis was markedly decreased. Further studies pointed to an intracellular neutrophil defect causing this motility dysfunction.Keywords
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