Cutis laxa is a rare condition characterized by hypertrophy and laxity of the skin and underlying connective tissue. The skin hangs in folds, thereby producing the clinical picture of premature senility in the affected person. Although relatively few definite examples of this syndrome have been published, the literature on the subject is extensive. As a result of numerous publications, the nomenclature associated with this condition is cluttered with confusing and unwieldy terms. The recent study of a case of cutis laxa in a 3½-year-old white girl prompted the following case report and a review of the literature. An attempt has been made to properly classify this unusual condition of unknown etiology. Report of a Case Pertinent History.—A girl aged 3½ years was referred for the first time for dermatologic consultation because of a defect in her skin which had been present since birth