Meningitis Due to Ceftriaxone-ResistantStreptococcus pneumoniae
- 30 March 1995
- journal article
- letter
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 332 (13), 893-894
- https://doi.org/10.1056/nejm199503303321317
Abstract
Penicillin-resistant strains of Streptococcus pneumoniae are found in many countries and are spreading, especially among children in day-care centers. Many authorities now recommend treating suspected cases of pneumococcal meningitis with ceftriaxone (or cefotaxime) and adding vancomycin, with or without rifampin, in communities where pneumococci highly resistant to penicillin are prevalent,1,2 because many such strains of pneumococci are not susceptible to ceftriaxone.3 In Providence, Rhode Island, only 2.3 percent of blood isolates of S. pneumoniae obtained at two hospitals in 1990 and 1991 had intermediate-level resistance to penicillin, and none were highly resistant.4 Hence, we presumed the prevalence of resistant strains in our area to be low.Keywords
This publication has 1 reference indexed in Scilit:
- High rate of erythromycin and clarithromycin resistance among Streptococcus pneumoniae isolates from blood cultures from Providence, R.IAntimicrobial Agents and Chemotherapy, 1993