Histological Studies of the Tissues of Rats Fed A Diet Extremely Low in Phosphorus

Abstract
Detailed microscopic studies have been made on tissues from rats restricted to a diet extremely low in phosphorus (0.017%) but adequate in all other respects. Marked skeletal rarefaction occurs with accompanying rickets. When the factor of inanition is excluded by paired feeding no other definite differences can be detected. The thymus gland and the reproductive system showed the effect of inanition most strongly. The results emphasize the importance of paired feeding in experiments of this nature.
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