THE INFLUENCE OF A PANCREAS EXTRACT ("FAT METABOLIZING HORMONE") UPON FAT DEPOSITION IN THE LIVER ON A LOW PROTEIN DIET

Abstract

More fat is deposited in the liver of [female] than [male] rats fed in a diet low in protein and high in fat. Under similar conditions young rats have a higher liver fat than old rats on such a diet. Oral administration of an alcoholic extract of pancreas believed to contain a fat metabolizing hormone caused a more rapid disappearance of fat stored in the livers on fasting and reduced the amount of fat in the liver of rats kept on the fatty liver producing diet.