Cumulative Meta-Analysis of Therapeutic Trials for Myocardial Infarction
- 23 July 1992
- journal article
- review article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 327 (4), 248-254
- https://doi.org/10.1056/nejm199207233270406
Abstract
The large volume of published randomized, controlled trials has led to a need for meta-analyses to track therapeutic advances. Performing a new meta-analysis whenever the results of a new trial of a particular therapy are published permits the study of trends in efficacy and makes it possible to determine when a new treatment appears to be significantly effective or deleterious. We describe the use of such a procedure, cumulative meta-analysis, to assess therapeutic trials among patients with myocardial infarction.Keywords
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