GENETIC LINKAGE BETWEEN OVALOCYTOSIS AND THE RH BLOOD TYPE 1

Abstract
A family of 28 members and 3 spouses were studied for the presence of ovalocytosis, the blood types and evidences for a hemolytic anemia. Ovalocytosis occurred as a simple autosomal Mendelian dominant. In each of 11 persons on whom complete data were obtained, the chromosomal distribution for the oval traits and the Rh pattern CDe (R1) were identical. The data indicated genetic linkage. No evidence of a hemolytic anemia was found.