A Comparison of the Relative Efficacy of CAPD and Hernodialysis in the Control of Solute Concentration

Abstract

Metabolite concentrations found in patients on both continuous ambulatory peritoneal dialysis (CAPD) and hemodialysis are predicted by means of a theoretical transport model. Effects of variation in parameters such as generation rate, mass transfer coefficients and residual renal clearance are studied. CAPD is as effective as hemodialysis in reducing the concentrations of low MW metabolites occurring in the "average" ESRD [end-stage renal dialysis] patient. CAPD becomes increasingly more effective than hemodialysis as MW increases.