Cystic Fibrosis: Characterization of the Inhibitor to Ciliary Action in Oyster Gills
- 6 February 1970
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 167 (3919), 871-873
- https://doi.org/10.1126/science.167.3919.871
Abstract
The inhibitor to oyster ciliary activity was isolated from serumof cystic fibrosis patients and heterozygotes.The inhibitinig protein fraction wast a cation as judged by electrophoresis; it had a molecuer weight of 125,000 to 200,000 as judged by gel filtration; antd oil diethylaminoethyl-cellulose chromatography it eluted with the immunoglobulin G fraction. The analogous fraction in normal individuals did not inhibit oyster cillary activity.Keywords
This publication has 5 references indexed in Scilit:
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- Oyster Ciliary Inhibition by Cystic Fibrosis FactorScience, 1969
- Abnormal Serum Factor in Patients with Cystic Fibrosis of the PancreasPediatric Research, 1967
- Estimation of the molecular weights of proteins by Sephadex gel-filtrationBiochemical Journal, 1964
- CHROMATOGRAPHY OF PROTEINS ON CELLULOSE ION-EXCHANGERSJournal of the American Chemical Society, 1954