The Functional Role of P-Glycoprotein in the Blood–Brain Barrier
- 1 August 1997
- journal article
- review article
- Published by American Geophysical Union (AGU) in Journal of Pharmaceutical Sciences
- Vol. 86 (8), 881-884
- https://doi.org/10.1021/js9701364
Abstract
No abstract availableThis publication has 20 references indexed in Scilit:
- Substantial excretion of digoxin via the intestinal mucosa and prevention of long‐term digoxin accumulation in the brain by the mdrla P‐glycoproteinBritish Journal of Pharmacology, 1996
- Altered Pharmacokinetics of Vinblastine in Mdr1a P-glycoprotein-Deficient MiceJNCI Journal of the National Cancer Institute, 1996
- P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs.Journal of Clinical Investigation, 1996
- The Blood-brain Barrier: Principles for Targeting Peptides and Drugs to the Central Nervous SystemJournal of Pharmacy and Pharmacology, 1996
- Isolation and culture of human brain microvessel endothelial cells for the study of blood-brain barrier properties in vitroBrain Research, 1995
- Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugsCell, 1994
- A method to determine the ability of drugs to diffuse through the blood-brain barrier.Proceedings of the National Academy of Sciences, 1994
- Osmotic blood-brain barrier disruption and chemotherapy in the treatment of high grade malignant glioma: patient series and literature reviewJournal of Neuro-Oncology, 1992
- Neurotoxicity of adriamycin passed through the transiently disrupted blood-brain barrier by mannitol in the rat brainBrain Research, 1987
- Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeabilityJournal of Medicinal Chemistry, 1980