STUDY OF A CASE OF APLASTIC ANEMIA

Abstract

By the term "aplastic anemia" is understood a type of anemia differing in many respects from ordinary types of primary or secondary anemia but marked especially by retrogressive changes in the bonemarrow which result in a change of the normal red marrow to a fatty marrow. The term was first used by Ehrlich¹ in 1888, in connection with an anemia of this type following severe uterine hemorrhage. Isolated examples of aplastic anemia have since been reported and in 1908 Cabot² collected reports of 24 authentic cases and discarded 11 other cases as incomplete or indefinite. In 1911 Hirschfeld³ in a discussion of the pathogenesis of the malady, gives briefly the essential features of 44 cases, of which 3 had been rejected and 12 accepted by Cabot. In the literature of the subject I have found 3 other cases, reported respectively by Crummer,⁴ by Stitt,