Lymphocyte Sensitization in Sarcoidosis

Abstract

Nineteen patients with sarcoidosis have all been shown to have lymphocytes in their blood sensitized to several antigens, including purified protein derivative of tuberculin and Kveim agent, though they had negative or greatly reduced Mantoux reaction. Two patients who repeatedly failed to “convert” after B.C.G. inoculation showed the same cell sensitization phenomena. No explanation can be offered for this anomaly.