Microbiological Assays and Bioautography of Maytansine and Its Homologues

Abstract
A quantitative microbiological assay and a bioautography system with Penicillium avellaneum UC-4376 was developed for the antitumor drugs maytansine, and its homologues, maytanprine and maytanbutine. The susceptibility of the assay is 1.5 μg/ml.

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