Hemagglutination-Inhibition and Serum Neutralization Response of Horses To Eastern Equine Encephalomyelitis Virus.

Abstract
Experimentally infected horses rapidly developed hemagglutination-inhibiting (HI) antibody, i.e., by the 5th day post-inoculation. None of these animals developed clinically recognizable disease. Natural cases of eastern equine encephalomyelitis (EEE) in horses are characterized by high HI titers at the time signs of central nervous system involvement appear. Neutralizing antibody for EEE virus persists longer than HI antibody as determined by a survey of horses in a post-epizootic area.