Peritoneal Mesothelioma in a Male Pseudohermaphrodite with Asymmetrical Gonadal Differentiation

Abstract

Bannayan, George A., Richardson, J. David, Short, Arvin D., and McFee, Arthur S.: Peritoneal mesothelioma in a male pseudohermaphrodite with asymmetrical gonadal differentiation. Am J Clin Pathol 69: 457–461,1978. A diffuse peritoneal mesothelioma occurring in a patient with male pseudohermaphroditism and asymmetrical gonadal differentiation (mixed gonadal dysgenesis) is described. Malignancies of mesodermal origin, usually derivatives of the urogenital ridge, appear to occur with increased frequency in male pseudo hermaphrodites. This appears to be the first reported instance of a mesothelioma in a male pseudohermaphrodite with mixed gonadal dysgenesis. The clinical and pathologic features of this tumor, including the electron microscopic findings, are presented.