Structure of the represser–operator complex of bacteriophage 434
- 1 April 1987
- journal article
- Published by Springer Nature in Nature
- Vol. 326 (6116), 846-852
- https://doi.org/10.1038/326846a0
Abstract
The crystal structure of a specific complex between the DNA-binding domain of phage 434 repressor and a synthetic 434 operator DNA shows interactions that determine sequence-dependent affinity. The repressor recognizes its operators by its complementarity to a particular DNA conformation as well as by direct interaction with base pairs in the major groove.Keywords
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